Early Prediction of Long-Term Renal Outcomes in Lupus Nephritis Using Hazard Index Equations

Tamirou, Farah;Houssiau, Frédéric;et.al.
(2018) 2018 ACR/ARHP Annual Meeting (22.October.2018)

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  • Tamirou, FarahUCLouvain
    Author
  • Houssiau, FrédéricUCLouvain
    Author
  • et. al.
Abstract
Early endpoints predicting long-term outcome in lupus nephritis (LN), which could be used as outcome measures in clinical trials, are still debated. Recently, a multicentric study, using an extended international database of prospectively followed LN patients, succeeded in computing equations (hazard index; HI) predicting adverse kidney outcomes, in casu chronic kidney disease (CKD), severe kidney injury (SKI) and renal replacement therapy (RRT). These HI were validated in a replicate cohort. The HI for CKD, SKI and RRT (calculated with data measured at one year) were significantly higher in groups with long-term poor renal outcomes after a follow-up (FU) of ≥ 4 years
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Tamirou, F., Houssiau, F., & et al. (2018). Early Prediction of Long-Term Renal Outcomes in Lupus Nephritis Using Hazard Index Equations. Arthritis & Rheumatology, 70. https://hdl.handle.net/2078.5/122384 (Original work published 2018)