LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells.
(1998) Infection and Immunity — Vol. 66, n° 6, p. 2976-2979 (1998)
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- Abstract
- Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.
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Sarker, M. R., Sory, M. P., Boyd, A. P., Iriarte, M., & Cornelis, G. R. (1998). LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells. Infection and Immunity, 66(6), 2976-2979. https://hdl.handle.net/2078.5/38908 (Original work published 1998)