Aldehydo-oligonucleotides for bioconjugation

Dechamps, Monique;Sonveaux, Etienne
(1998) Nucleosides and Nucleotides — Vol. 17, n° 4, p. 697-709 (1998)

Files

No attached file found for this publication.

Details

Authors
  • Dechamps, MoniqueUCLouvain
    Author
  • Sonveaux, EtienneUCLouvain
    Author
Abstract
The synthesis of a new phosphoramidite building block with a masked aldehyde function is described. It was incorporated in an oligodeoxyribonucleotide. Coupling to amino derivatives by reductive amination was performed in high yield after unmasking the aldehyde function.
Affiliations

Citations

Dechamps, M., & Sonveaux, E. (1998). Aldehydo-oligonucleotides for bioconjugation. Nucleosides and Nucleotides, 17(4), 697-709. https://doi.org/10.1080/07328319808004669 (Original work published 1998)