When density fails to predict bone strength

Banse, Xavier
(2002)

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Authors
  • Banse, XavierUCLouvain
    author
Supervisors
Munting, Everard
 ;
Delloye, Christian
Abstract
This review is the report of a single experimental protocol on the nature, structure and mechanical strength of 136 bones samples from the vertebral body of 9 subjects. On these samples, we combined mechanical testing with density measurements (Part I), a study of some microarchitectural parameters (part II) and a biochemical analysis of bone collagen (part III). As multiple samples were studied in each subject we explored whether a given parameter was characteristic of that subject. The parameters ware also systematically screened as potential indicators of the bone quality. The association of biochemical and microarchitectural data offered a unique opportunity to compare both sets of data (part IV). Finally, in a technical addendum, we report the comparison of histology vs pQCT (a small scanner) as investigation tools for the bone density and microarchitecture
Affiliations
  • Institution iconUCLouvainMD/MED/CHIR - Département de chirurgie

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Banse, X. (2002). When density fails to predict bone strength. https://hdl.handle.net/2078.5/110861