Identifying, Characterizing, and Understanding Nefiracetam in Its Solid State Forms: A Potential Antidementia Drug
(2019) Journal of Pharmaceutical Sciences — Vol. 108, n° 11, p. 3616-3622 (2019)
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- Authors
TUMANOV, Nikolay 
- Abstract
- In this work, 3 hitherto unidentified solid state forms of the nootropic drug Nefiracetam are identified: a monohydrate and 2 polymorphic phases of the anhydrate. These new forms were investigated from a structural and thermodynamic point of view to evaluate the possibility of using these forms in alternative formulations. Furthermore, their dissolution rate and solubility were compared.
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Citations
Buol, X., Robeyns, K., TUMANOV, N., Wouters, J., & Leyssens, T. (2019). Identifying, Characterizing, and Understanding Nefiracetam in Its Solid State Forms: A Potential Antidementia Drug. Journal of Pharmaceutical Sciences, 108(11), 3616-3622. https://doi.org/10.1016/j.xphs.2019.07.010 (Original work published 2019)