Structural Basis for Force Decline in Edl-muscle From Mdx Mice After Eccentric Contraction

Baatsen, P.;Moens, P.;Maréchal, Georges
(1993)

Files

M130PDF.pdf
  • Open Access
  • Adobe PDF
  • 105.69 KB
Download

Details

Authors
  • Baatsen, P.
    Author
  • Moens, P.UCLouvain
    Author
  • Maréchal, GeorgesUCLouvain
    Author
Abstract
(en) EDL-muscles from mdx mice display an irreversible decline in maximal isometric force after eccentric contractions (Moens et al., J MRCM, 14, 446-51). About 50% of the force decline could be explained by membrane-damaged fibres. The unexplained part of the force decline could be caused by damage at the myotendinous junction (MTJ). Ultrathin longitudinal sections were cut at 100 µm intervals from blocks that contained both tendon and muscle. No fibres display separation of basement- and plasma membrane at the MTJ. Our results indicate yet another cause for the unexplained part of the force decline observed after eccentric contractions in EDL muscles from mdx mice.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Baatsen, P., Moens, P., & Maréchal, G. (1993). Structural Basis for Force Decline in Edl-muscle From Mdx Mice After Eccentric Contraction. Journal of Muscle Research and Cell Motility, 14(2), 255. (Original work published 1993)