The value of reconstructive surgery in the management of refractory jaw osteoradionecrosis: a single-center 10-year experience
(2019) International Journal of Oral and Maxillofacial Surgery — Vol. 48, n° 11, p. 1398-1404 (2019)
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- Authors
Bettoni, Jérémie 
- Abstract
- Mandibular osteoradionecrosis (mORN) is a severe complication of head and neck irradiation. International consensus on the management of mORN is currently lacking. The present study sought to evaluate the effectiveness and benefits of early reconstructive surgery (resection of the diseased bone and immediate reconstruction with a free flap) in treatment-refractory mORN. A single-center retrospective study was carried out of operations performed in a French university medical center between 2003 and 2013 inclusive. For each patient, the surgical modalities and postoperative outcomes were recorded. A total of 55 operations (19 marginal resections and 36 segmental resections) were performed, and the overall success rate was 92.3%. Relative to marginal resections, segmental resections were associated with longer operating times (440±62min vs. 531±72min, respectively; P<0.05 in Student's t-test), a longer length of hospital stay (16.5±6.5 days vs. 25.6±11.3 days, respectively; P<0.05), and a higher complication rate (26.3% vs. 63.9%, respectively; P<0.05 in Fisher's test). Given the unpredictable progression of treatment-refractory mORN and the risk-benefit ratio observed here, the value of early reconstructive surgery with curative intent should be reassessed.
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Citations
Bettoni, J., Olivetto, M., Duisit, J., Caula, A., Testelin, S., Dakpé, S., Lengelé, B., & Devauchelle, B. (2019). The value of reconstructive surgery in the management of refractory jaw osteoradionecrosis: a single-center 10-year experience. International Journal of Oral and Maxillofacial Surgery, 48(11), 1398-1404. https://doi.org/10.1016/j.ijom.2019.06.007 (Original work published 2019)