The lysosome turns fifty.
(2005) Nature Cell Biology — Vol. 7, n° 9, p. 847-849 (2005)
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- Authors
- Abstract
- In the course of an investigation aimed at characterizing hepatic glucose 6-phosphatase, the unrelated acid phosphatase of rat liver was serendipitously observed to be latent and particle-bound in freshly prepared homogenates. Experiments designed to elucidate this intriguing finding led, 50 years ago, to the discovery of lysosomes. This could not have happened if strict adherence to a previously set programme had been mandatory.
- Affiliations
New-York Rockefeller University
Citations
De Duve, C. (2005). The lysosome turns fifty. Nature Cell Biology, 7(9), 847-849. https://doi.org/10.1038/ncb0905-847 (Original work published 2005)