The potential role of targeted therapies in the management of neuroendocrine tumours

Verset, G.;Borbath, Ivan;Pauwels, Stanislas;Delaunoit, T.;Van Laethem, J. L.;et.al.
(2009) Acta Gastro-Enterologica Belgica (Multilingual Edition) — Vol. 72, n° 1, p. 59-62 (2009)

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Authors
  • Verset, G.
    Author
  • Borbath, IvanUCLouvain
    Author
  • Pauwels, StanislasUCLouvain
    Author
  • Delaunoit, T.
    Author
  • Author
  • Peeters, Marie-RoseUCLouvain
    Author
  • Van Cutsem, EmmanuelUCLouvain
    Author
  • Verslype, C.UCLouvain
    Author
  • Van Laethem, J. L.
    Author
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Abstract
The management of gastro-entero-pancreatic neuroendocrine tumours is evolving thanks to new TNM-classification, diagnostic and staging procedures and new therapeutic options. Targeting new pathways, mostly angiogenesis, development of novel agents is under way and opens new perspectives in controlling the evolution of these tumours and possibly changing their management. In parallel, new functional imaging techniques and biomolecular markers will be developed to provide adequate tools for the assessment of tumor response according to therapeutic intervention on angiogenesis, proliferation and apoptosis. This paper reviews the potential role of new investigational targeted agents which will likely become the backbone of future therapy of neuroendocrine tumors. (Acta gastroenterol. belg., 2009, 72,59-62).
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Citations

Verset, G., Borbath, I., Pauwels, S., Delaunoit, T., Demetter, P., Demolin, G., Hendlisz, A., Pattyn, P., Peeters, M.-R., Roeyen, G., Van Cutsem, E., Van Hootegem, Ph., Verslype, C., & Van Laethem, J. L. (2009). The potential role of targeted therapies in the management of neuroendocrine tumours. Acta Gastro-Enterologica Belgica (Multilingual Edition), 72(1), 59-62. https://hdl.handle.net/2078.5/211633 (Original work published 2009)