Relationship between supramaximal flows and flow-limiting mechanisms
(1996) The European Respiratory Journal — Vol. 9, n° 3, p. 512-516 (1996)
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- Abstract
- The aim of this study was to evaluate the relationship between supramaximal flows (SF) and indices of airway mechanics. We studied 26 asymptomatic young subjects (13 smokers, mean+/-SD 15.9+/-6.6 pack-years). Subjects performed maximal expiratory now-volume (MEFV) curves, according to the American Thoracic Society (ATS) criteria, on a rolling-seal spirometer and then repeated them through a specially devised valve, which occluded the mouthpiece either 3 or 6 times . s(-1) with a ratio of open:closed time of 3:1, Envelope MEFV curves for 3 and 6 Hz occlusions were constructed passing through the SF obtained after each occlusion, and the increment in now at 50% of vital capacity was measured with respect to the basal curve (Delta V'max50). We found that the Delta V'max50 at 3 and 6 Hz correlated to the baseline forced mid-expiratory flow (FEF25-75) in % of predicted value (r=-0.73 and r=-0.55, respectively). Our results suggest that inhomogeneities within the lung are an important mechanism in the occurrence of supramaximal flow in normal subjects. (C)ERS Journals 1996.
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Sala, H., Galindez, F., Badolati, A., & Rodenstein, G. (1996). Relationship between supramaximal flows and flow-limiting mechanisms. The European Respiratory Journal, 9(3), 512-516. https://doi.org/10.1183/09031936.96.09030512 (Original work published 1996)