IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation.

Takahashi, Kentaro;Hirose, Koichi;Kawashima, Saki;Niwa, Yusuke;Nakajima, Hiroshi;et.al.
(2011) Journal of Allergy and Clinical Immunology — Vol. 128, n° 5, p. 1067-1076 (2011)

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Authors
  • Takahashi, Kentaro
    Author
  • Hirose, Koichi
    Author
  • Kawashima, Saki
    Author
  • Niwa, Yusuke
    Author
  • Nakajima, Hiroshi
    Author
  • et. al.
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Abstract
IL-22 functions as both a proinflammatory cytokine and an anti-inflammatory cytokine in various inflammations, depending on the cellular and cytokine milieu. However, the roles of IL-22 in the regulation of allergic airway inflammation are still largely unknown.
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Citations

Takahashi, K., Hirose, K., Kawashima, S., Niwa, Y., Wakashin, H., Iwata, A., Tokoyoda, K., Renauld, J.-C., Iwamoto, I., Nakayama, T., Nakajima, H., & et al. (2011). IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation. Journal of Allergy and Clinical Immunology, 128(5), 1067-1076. https://doi.org/10.1016/j.jaci.2011.06.018 (Original work published 2011)