The FtsK DNA-translocase controls the last steps of chromosome segregation in E. coli. It translocates sister chromosomes using the KOPS DNA motifs to orient its activity, and controls the resolution of dimeric forms of sister chromosomes by XerCD-mediated recombination at the dif site and their decatenation by TopoIV.
Affiliations
UCLouvainSST/ISV - Institut des sciences de la vie
Deghorain, M., Pagès, C., Meile, J.-C., Stouf, M., Capiaux, H., Mercier, R., Lesterlin, C., Hallet, B., & Cornet, F. (2011). A defined terminal region of the E. coli chromosome shows late segregation and high FtsK activity. PLoS One, 6(7), e22164. https://doi.org/10.1371/journal.pone.0022164 (Original work published 2011)