The enzymatic and mass spectrometric identification of 2-oxophytanic acid, a product of the peroxisomal oxidation of l-2-hydroxyphytanic acid.
(1988) Biomedical and Environmental Mass Spectrometry — Vol. 15, n° 6, p. 345-351 (1988)
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- Abstract
- A previously unreported metabolite of the mammalian phytanic acid breakdown pathway, 2-oxophytanic acid, was isolated and analysed by mass spectrometry. The metabolic origin of the 2-oxoacid is the oxidation by a rat kidney peroxisomal H2O2-generating oxidase of L-2-hydroxyphytanic acid, a well-established intermediate in phytanic acid alpha-oxidation.
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Vamecq, J., & Draye, J.-P. (1988). The enzymatic and mass spectrometric identification of 2-oxophytanic acid, a product of the peroxisomal oxidation of l-2-hydroxyphytanic acid. Biomedical and Environmental Mass Spectrometry, 15(6), 345-351. https://doi.org/10.1002/bms.1200150607 (Original work published 1988)