A rapid screening test to distinguish between Candida albicans and Candida dubliniensis using NMR spectroscopy

Himmelreich, Uwe;Somorjai, Ray L;Dolenko, Brion;Daniel, Heide-Marie;Sorrell, Tania C
(2005) FEMS Microbiology Letters — Vol. 251, n° 2, p. 327-332 (2005)

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Authors
  • Himmelreich, UweUniversity of Sydney at Westmead Hospital, Australia
    Author
  • Somorjai, Ray LInstitute for Biodiagnostics, Canada
    Author
  • Dolenko, BrionInstitute for Biodiagnostics, Canada
    Author
  • Daniel, Heide-MarieUCLouvain
    Collaborator
  • Sorrell, Tania CUniversity of Sydney at Westmead Hospital, Australia
    Author
Abstract
Nuclear magnetic resonance (NMR) spectroscopy combined with a statistical classification strategy (SCS) successfully distinguished between Candida albicans and Candida dubliniensis. 96% of the isolates from an independent test set were identified correctly. This proves that this rapid approach is a valuable method for the identification and chemotaxonomic characterisation of closely related taxa. Most discriminatory regions were correlated with metabolite profiles, indicating biochemical differences between the two species. (C) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Affiliations
  • University of Sydney at Westmead HospitalCentre for Infectious Diseases and Microbiology (CIDM)
  • National Research Council CanadaInstitute for Biodiagnostics

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Himmelreich, U., Somorjai, R. L., Dolenko, B., & Sorrell, T. C. (2005). A rapid screening test to distinguish between Candida albicans and Candida dubliniensis using NMR spectroscopy. FEMS Microbiology Letters, 251(2), 327-332. https://doi.org/10.1016/j.femsle.2005.08.016 (Original work published 2005)