The cycloaddition of diazoazoles with acylisothiocyanates has been found to result in the formation of a 1,2,3,5-thiatriazine ring. This new reaction was used to prepare novel 8-substituted 4-[benzoylimino-4H-imidazo(pyrazolo)][5,1-d] -[1,2,3,5]thiatriazines. The structures of the compounds prepared were carefully studied by X-ray diffraction, IR and NMR spectroscopy.
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KU LEUVENDepartment of Chemistry
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Sadchikova, E. V., Bakulev, V. A., Dehaen, W., Van Hecke, K., Robeyns, K., Van Meervelt, L., Mokrushin, V. S., & Padwa, A. (2004). Synthesis of novel azolo[1,2,3,5]thiatriazines. Synlett : accounts and rapid communications in synthetic organic chemistry, 11(11), 2037-2039. https://doi.org/10.1055/s-2004-830895 (Original work published 2004)