25P Association between the lung immune prognostic index (LIPI) and durvalumab consolidation outcomes in patients with locally advanced non-small cell lung cancer (NSCLC)
BACKGROUND : The LIPI, based on pretreatment derived neutrophils/[leukocytes-neutrophils] ratio (dNLR) >3 and lactate dehydrogenase (LDH) >upper limit of normal (ULN), is associated with immune checkpoint inhibitors (ICI) outcomes in advanced non-small cell lung cancer (NSCLC). We aimed to assess if baseline LIPI correlates with durvalumab efficacy after chemoradiotherapy (ChRT) in the locally advanced setting. [...]
Riudavets Melia, M., Auclin, E., Aboubakar Nana, F., Ponce Aix, S., Dal Maso, A., Bluthgen, V., Mielgo, X., Mussat, E., Reyes, R., Benítez, J., Lupinacci, L., Duchemann, B., de Giglio, A., Bautista, J., Audigier-Valette, C., Scheffler, M., Campayo, M., Besse, B., Planchard, D., & Mezquita, L. (2021). 25P Association between the lung immune prognostic index (LIPI) and durvalumab consolidation outcomes in patients with locally advanced non-small cell lung cancer (NSCLC). Annals of Oncology, 32(Suppl 7), S1384. https://doi.org/10.1016/j.annonc.2021.10.041 (Original work published 2021)