The epithelial Na+ channel: progressing from Liddle's syndrome to essential hypertension

Persu, Alexandre
(2003) Journal of Hypertension — Vol. 21, n° 5, p. 855-857 (2003)

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Comment on Loss of protein kinase C inhibition in the beta-T594M variant of the amiloride-sensitive Na+ channel. [Proc Natl Acad Sci U S A. 1997] A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension. [J Hypertens. 2003] A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients. [J Clin Endocrinol Metab. 2003]
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Persu, A. (2003). The epithelial Na+ channel: progressing from Liddle’s syndrome to essential hypertension. Journal of Hypertension, 21(5), 855-857. https://doi.org/10.1097/00004872-200305000-00004 (Original work published 2003)