The OMERACT MRI in Enthesitis Initiative: Definitions of Key Pathologies, Suggested MRI Sequences, and a Novel Heel Enthesitis Scoring System.
(2019) Journal of Rheumatology — Vol. 46, n° 9, p. 1232-1238 (2019)
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- Authors
Mathew, Ashish J 
Krabbe, Simon Eshed, Iris Gandjbakhch, Frédérique Østergaard, Mikkel
- Abstract
- OBJECTIVE: To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. METHODS: Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. RESULTS: Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. CONCLUSION: The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.
- Affiliations
Citations
Mathew, A. J., Krabbe, S., Eshed, I., Gandjbakhch, F., Bird, P., Pedersen, S. J., Stoenoiu, M., Foltz, V., Glinatsi, D., Lambert, R. G., Hermann, K. G. A., Maksymowych, W. P., Haugen, I. K., Jaremko, J. L., Poggenborg, R. P., Paschke, J., Laredo, J.-D., Carron, P., Conaghan, P. G., & Østergaard, M. (2019). The OMERACT MRI in Enthesitis Initiative: Definitions of Key Pathologies, Suggested MRI Sequences, and a Novel Heel Enthesitis Scoring System. Journal of Rheumatology, 46(9), 1232-1238. https://doi.org/10.3899/jrheum.181093 (Original work published 2019)