A systematic review and meta-analysis of patient-specific instrumentation for improving alignment of the components in total knee replacement
(2014) The Bone & Joint Journal — Vol. 96 B, n° 8, p. 1052-1061 (2014)
Files
No attached file found for this publication.
Details
- Authors
- Abstract
- We conducted a meta-analysis, including randomised controlled trials (RCTs) and cohort studies, to examine the effect of patient-specific instruments (PSI) on radiological outcomes after total knee replacement (TKR) including: mechanical axis alignment and malalignment of the femoral and tibial components in the coronal, sagittal and axial planes, at a threshold of > 3° from neutral. Relative risks (RR) for malalignment were determined for all studies and for RCTs and cohort studies separately. Of 325 studies initially identified, 16 met the eligibility criteria, including eight RCTs and eight cohort studies. There was no significant difference in the likelihood of mechanical axis malalignment with PSI versus conventional TKR across all studies (RR = 0.84, p = 0.304), in the RCTs (RR = 1.14, p = 0.445) or in the cohort studies (RR = 0.70, p = 0.289). The results for the alignment of the tibial component were significantly worse using PSI TKR than conventional TKR in the coronal and sagittal planes (RR = 1.75, p = 0.028; and RR = 1.34, p = 0.019, respectively, on pooled analysis). PSI TKR showed a significant advantage over conventional TKR for alignment of the femoral component in the coronal plane (RR = 0.65, p = 0.028 on pooled analysis), but not in the sagittal plane (RR = 1.12, p = 0.437). Axial alignment of the tibial (p = 0.460) and femoral components (p = 0.127) was not significantly different. We conclude that PSI does not improve the accuracy of alignment of the components in TKR compared with conventional instrumentation. ©2014 The British Editorial Society of Bone & Joint Surgery.
- Affiliations
Citations
Thienpont, E., Schwab, P.-E., & Fennema, P. (2014). A systematic review and meta-analysis of patient-specific instrumentation for improving alignment of the components in total knee replacement. The Bone & Joint Journal, 96 B(8), 1052-1061. https://doi.org/10.1302/0301-620X.96B8.33747 (Original work published 2014)