Post-transplant lymphoproliferative disorder after kidney transplantation: time to adopt monitoring of Epstein-Barr virus?

Biller, Pauline;Michaux, Lucienne;De Pauw, Luc;Camboni, Alessandra;Kanaan, Nada;et.al.
(2015) Acta Clinica Belgica — Vol. 70, n° 3, p. 218-222 (2015)

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Authors
  • Biller, PaulineUCLouvain
    Author
  • Michaux, LucienneUCLouvain
    Author
  • De Pauw, LucUCLouvain
    Author
  • Camboni, AlessandraUCLouvain
    Author
  • Mourad, MichelUCLouvain
    Author
  • Kanaan, NadaUCLouvain
    Author
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Abstract
Although post-transplant lymphoproliferative disorder is a classical complication encountered after kidney transplantation, its diagnosis can still be challenging and its outcome life-threatening. Most cases are related to Epstein-Barr virus (EBV) infection and occur mainly in the first year post-transplant, favoured by the seronegative EBV status of the recipient transplanted with a kidney from a seropositive donor, and strong immunosuppression. We report the case of a young kidney-pancreas transplant recipient who developed post-transplant lymphoproliferative disorder (PTLD) early after transplantation, with a rapid fatal issue. We review the pathogenesis, clinical presentation, and management of PTLD with a focus on prevention.
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Biller, P., Michaux, L., De Pauw, L., Camboni, A., Mourad, M., & Kanaan, N. (2015). Post-transplant lymphoproliferative disorder after kidney transplantation: time to adopt monitoring of Epstein-Barr virus? Acta Clinica Belgica, 70(3), 218-222. https://doi.org/10.1179/2295333714Y.0000000112 (Original work published 2015)