Clostridium difficile infection: Early history, diagnosis and molecular strain typing methods.

Rodriguez, Cristina;Van Broeck, Johan;Taminiau, Bernard;Delmée, Michel;Daube, Georges
(2016) Microbial Pathogenesis — Vol. 97, p. 59-78 (2016)

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Authors
  • Rodriguez, Cristina
    Author
  • Van Broeck, JohanUCLouvain
    Author
  • Taminiau, Bernard
    Author
  • Author
  • Daube, Georges
    Author
Abstract
Recognised as the leading cause of nosocomial antibiotic-associated diarrhoea, the incidence of Clostridium difficile infection (CDI) remains high despite efforts to improve prevention and reduce the spread of the bacterium in healthcare settings. In the last decade, many studies have focused on the epidemiology and rapid diagnosis of CDI. In addition, different typing methods have been developed for epidemiological studies. This review explores the history of C. difficile and the current scope of the infection. The variety of available laboratory tests for CDI diagnosis and strain typing methods are also examined.
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Citations

Rodriguez, C., Van Broeck, J., Taminiau, B., Delmée, M., & Daube, G. (2016). Clostridium difficile infection: Early history, diagnosis and molecular strain typing methods. Microbial Pathogenesis, 97, 59-78. https://doi.org/10.1016/j.micpath.2016.05.018 (Original work published 2016)