Peripheral nerve blockade and neonatal limb ischemia: our experience and literature review.
(2014) Clinical and Applied Thrombosis / Hemostasis — Vol. 20, n° 1, p. 55-60 (2014)
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- Authors
- Abstract
- Considering the high frequency of bleeding complications following fibrinolytic treatment in neonates, peripheral nerve blockade (PNB) has been proposed alone or in association with lower doses of tissue plasminogen activator, as a possible new therapeutic approach in the management of neonatal limb ischemia (LI) secondary to vasospasm and/or thrombosis. The present article provides a review of the current knowledge about the topic, in order to evaluate the efficacy and safety of this therapeutic approach. According to the few case reports documented in literature and to our experience, PNB could be considered as valid procedure for the treatment of LI, especially during neonatal period, when the risk of serious bleeding associated with fibrinolytic or anticoagulant therapy is higher. Peripheral nerve blockade resulted in a safe and effective procedure for the treatment of neonatal vascular spasm and thrombosis.
- Affiliations
Bambino Gesù Children’s Hospital – (Italy) Roma Department of Medical and Surgical Neonatology
Citations
De Carolis, M. P., Bersani, I., Piersigilli, F., Rubortone, S. A., Occhipinti, F., Lacerenza, S., & Romagnoli, C. (2014). Peripheral nerve blockade and neonatal limb ischemia: our experience and literature review. Clinical and Applied Thrombosis / Hemostasis, 20(1), 55-60. https://doi.org/10.1177/1076029612458968 (Original work published 2014)