A stereoselective synthesis of the polyene fragment C(53)-C(67) of amphidinol 3 is described using a sequence of reduction, benzoylation, and reductive elimination for the stereospecific preparation of the polyene motif as key steps starting from acetylenic precursors.
Colobert, F., Kreuzer, T., Cossy, J., Reymond, S., Tsuchiya, T., Ferrie, L., Marko, I., & Jourdain, P. (2007). Stereoselective synthesis of the C(53)-C(67) polyene fragment of amphidinol 3. Synlett : accounts and rapid communications in synthetic organic chemistry, 15, 2351-2354. https://doi.org/10.1055/s-2007-985601 (Original work published 2007)