Stereoselective synthesis of the C(53)-C(67) polyene fragment of amphidinol 3

Colobert, Francoise;Kreuzer, Thomas;Cossy, Janine;Reymond, Sebastien;Jourdain, Pierre;et.al.
(2007) Synlett : accounts and rapid communications in synthetic organic chemistry — n° 15, p. 2351-2354 (2007)

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  • Colobert, Francoise
    Author
  • Kreuzer, Thomas
    Author
  • Cossy, Janine
    Author
  • Reymond, Sebastien
    Author
  • Marko, IstvanUCLouvain
    Author
  • Jourdain, PierreUCLouvain
    Author
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Abstract
A stereoselective synthesis of the polyene fragment C(53)-C(67) of amphidinol 3 is described using a sequence of reduction, benzoylation, and reductive elimination for the stereospecific preparation of the polyene motif as key steps starting from acetylenic precursors.
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Colobert, F., Kreuzer, T., Cossy, J., Reymond, S., Tsuchiya, T., Ferrie, L., Marko, I., & Jourdain, P. (2007). Stereoselective synthesis of the C(53)-C(67) polyene fragment of amphidinol 3. Synlett : accounts and rapid communications in synthetic organic chemistry, 15, 2351-2354. https://doi.org/10.1055/s-2007-985601 (Original work published 2007)