[Mechanical performances of striated muscle poisoned with 1-fluoro-2,4-dinitrobenzene].
(1968) Journal de Physiologie — Vol. 60, n° Suppl 2, p. 357 (1968)
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- Abstract
- Sartorius muscles of frogs, poisoned with 1-fluoro-2,4-dinitro-benzene (FDNB, which inhibits creatinephosphokinase)) are tetanized for two seconds six times at 6 minutes apart, at 0 ° C. The muscles are shortened during tetanus at a velocity controlled by a pneumatic ergometer, and the force Pr maintained at a given speed is related to the isometric force Pm maintained just before the shortening. The force-velocity relation was defined by the exponential equation of AUBERT (1956). The repetition of tetanus does not change the velocity constant B but increases linearly the “friction” force f. FDNB increases the effect of tetanus repetition on the force constant f by approximately four times, without modifying the velocity constant B.
Citations
Dumoulin, C., & Maréchal, G. (1968). [Mechanical performances of striated muscle poisoned with 1-fluoro-2,4-dinitrobenzene]. Journal de Physiologie, 60(Suppl 2), 357. https://hdl.handle.net/2078.5/214165 (Original work published 1968)