BACKGROUND: The early development of complications in twin-twin transfusion syndrome is a poor prognostic sign. For this reason, new techniques for intrauterine therapy are being developed: invasive options, such as selective feticide of one of the twins, have been reported. CASES: Two cases of twin-twin transfusion syndrome in the late second trimester were treated by selective feticide using vascular embolization to the move severely damaged fetus. In one case the embolized fetus was a hydropic recipient with a normal cotwin; in the other, the donor fetus pins affected by bilateral hydrocephalus. These fetuses underwent ultrasound-guided embolization using a bolus of histoacryl injected into the umbilical vein and fetal heart. Both patients went on to deliver healthy singletons in the third trimester. CONCLUSION: In twin-twin transfusion syndrome of early onset, embolization may help one of the twins survive. This technique is neither time-consuming nor expensive and does not require a general anesthetic.
Donner, C., Shahabi, S., Thomas, D., Noël, JC., Kirkpatrick, C., VanRysselberghe, M., Hubinon, C., Vermeylen, D., Masters, L., & Rodesch, F. (1997). Selective feticide by embolization in twin-twin transfusion syndrome - A report of two cases. Journal of Reproductive Medicine : for the obstetrician and gynecologist, 42(11), 747-750. https://hdl.handle.net/2078.5/85730 (Original work published 1997)