Pig to monkey bone marrow and kidney xenotransplantation.

Sablinski, T;Gianello, Pierre;Bailin, M;Bergen, K S;Sachs, D H;et.al.
(1997) Surgery — Vol. 121, n° 4, p. 381-391 (1997)

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Authors
  • Sablinski, T
    Author
  • Gianello, PierreUCLouvain
    Author
  • Bailin, M
    Author
  • Bergen, K S
    Author
  • Sachs, D H
    Author
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Abstract
The intensity of discordant xenograft cellular rejection makes it unlikely that safe doses of immunosuppressive drugs will alone be sufficient to permit long-term survival. We have therefore concentrated our efforts on establishing tolerance to xenogeneic organs through lymphohematopoietic chimerism and the elimination of preformed natural antibodies (nAbs).
Affiliations
  • Harvard Medical SchoolTransplantation Biology Research Center, MGH, Boston

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Sablinski, T., Gianello, P., Bailin, M., Bergen, K. S., Emery, D. W., Fishman, J. A., Foley, A., Hatch, T., Hawley, R. J., Kozlowski, T., Lorf, T., Meehan, S., Monroy, R., Powelson, J. A., Colvin, R. B., Cosimi, A. B., & Sachs, D. H. (1997). Pig to monkey bone marrow and kidney xenotransplantation. Surgery, 121(4), 381-391. https://hdl.handle.net/2078.5/38919 (Original work published 1997)