Brain structural markers improve prediction of cochlear implant outcomes in postlingual deafness
(2025)
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- Abstract
- Severe deafness is a common public health issue, and its prevalence is expected to increase in the coming years. Cochlear implantation offers an effective solution when conventional hearing aids are no longer sufficient. However, despite generally positive outcomes, there remains significant interindividual variability, which is still poorly understood. The aim of this thesis is to better identify the factors underlying this variability, using preoperative MRI. First, a meta-analysis of the literature revealed grey and white matter alterations surrounding the auditory areas in deaf individuals. The second study showed a correlation between grey matter volume in auditory and language-related regions and post-implantation performance. Finally, our third article demonstrated that the analysis of white matter, particularly in the arcuate fasciculus, can also help estimate speech outcomes. These findings highlight the value of preoperative MRI measures in identifying patients at risk of suboptimal outcomes, in order to tailor their care more effectively.
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Grégoire, A. (2025). Brain structural markers improve prediction of cochlear implant outcomes in postlingual deafness. https://hdl.handle.net/2078.5/256538