Evaluation of cryopreserved ovarian tissue from prepubertal patients after long-term xenografting and exogenous stimulation.
(2013) Fertility and sterility — p. 1-9 (2013)
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- Abstract
- This is the first description of transplantation of human cryopreserved prepubertal ovarian tissue to mice, demonstrating that a very high number of follicles survive after transplantation and a large pool of primordial follicles remains dormant. Growing follicles were observed, proving the responsiveness of prepubertal ovarian tissue to gonadotropins.
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Luyckx, V., Rocha De Azevedo Scalercio, S., Jadoul, P., Andrade Amorim, C., Soares, M., Donnez, J., & Dolmans, M.-M. (2013). Evaluation of cryopreserved ovarian tissue from prepubertal patients after long-term xenografting and exogenous stimulation. Fertility and sterility, 1-9. https://doi.org/10.1016/j.fertnstert.2013.07.202 (Original work published 2013)