Prise en charge de l’hémophilie en salle d’urgence
(2012) Annales françaises de médecine d’urgence — Vol. 2, n° 4, p. 256-264 (2012)
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- (en) Hemophilia is a rare genetic disorder caused by a deficiency in coagulation factor VIII or IX. The disease is responsible for spontaneous or induced haemorrhages, depending on the severity of the clotting factor deficiency. The admission of a hemophilic patient in the emergency department is not frequent, not only because of the the disorder's rarety, but also due to the availability of new effective treatment options including self-treatment at home. Over a twelve-months period, only 0,05% of emergency department admissions in a university hospital in Brussels concerned hemophilic patients. Thus, the emergency department physician is rarely confronted with a hemophilic patient in the event of a hemorrhagic incident, and equally for any other acute medical problem whose management should be adapted to the haemophilic patient. The ED physician should recognise haemophilia when a patient, not known to be haemophilic, presents to the emergency department with haemorrhagic complications. This article reviews the principal physiopathological mechanisms of haemophilia, the available treatment options, and summarizes the main therapeutic recommendations. It aims to provide the ED physician with the useful information required for an optimal management of haemophilia in the emergency setting.
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Tutus, C., Thys, F., & Hermans, C. (2012). Prise en charge de l’hémophilie en salle d’urgence. Annales françaises de médecine d’urgence, 2(4), 256-264. https://doi.org/10.1007/s13341-012-0189-6 (Original work published 2012)