We describe three cases of multiple endocrine neoplasia type I (Wermer’s syndrome) associating a pituitary, parathyroid and pancreatic tumour in various combinations. In the first patient, a prolactinoma was originally diagnosed and, 6 years later, an insulinoma was discovered; in the same time, strong biological evidence for a gastrinoma and hyperparathyroidism was found. The second case presented with parathyroid adenoma and a probable mixed and diffuse pancreatic tumour. In the third patient, acromegaly was associated with diffuse parathyroid hyperplasia. We emphasize in these three cases the great variety of clinical and biological presentations of polyadenomatosis type I
Maiter, D., Lambert, M., Alhajje, A., Dugernier, T., Crabbé, J., & Fiasse, R. (1986). Multiple Endocrine Neoplasia Type-i (men-i) - a Wide-range of Clinical Presentation - Report of 3 Cases. Acta Clinica Belgica (Multilingual Edition), 41(2), 89-95. https://doi.org/10.1080/22953337.1986.11719131 (Original work published 1986)