Bio-inorganic hybrid catalyst combining enzyme aggregates and catalytic hollow spheres for the green epoxidation of olefins
(2018) 7th EuCheMS Chemistry Congress — Location: Liverpool, UK (26.August.2018)
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- Authors
Smeets, Valentin 
- Abstract
- In line with green chemistry principles, Vennestrom et al. proposed the chemoenzymatic epoxidation of olefins by sequential catalysis using glucose oxidase (GOx) - for in situ production of H2O2 - and microporous titanosilicalite-1 (TS-1). The direct immobilization of GOx on the catalyst was also proposed but the epoxide production was notably limited by the low enzyme loading. Here, we propose a new strategy for the preparation of a hybrid catalyst that combines all the features of TS-1 with a high loading of GOx. The method is based on the aerosol-assisted self-assembly of TS-1 nanocrystals to form hollow spheres with tailored texture and good epoxidation activity. These spheres are subsequently loaded with the enzymes which are then cross-linked to secure their entrapment. Upon optimization of the working conditions, we show that it is possible to reach much higher epoxide productivity.
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Citations
Smeets, V., Boissière, C., Baaziz, W., Ersen, O., Gaigneaux, E., Sanchez, C., & Debecker, D. (2018). Bio-inorganic hybrid catalyst combining enzyme aggregates and catalytic hollow spheres for the green epoxidation of olefins. 7th EuCheMS Chemistry Congress, Liverpool, UK. https://hdl.handle.net/2078.5/61446