(en) The incidental discovery of an adrenal lesion should prompt the clinician to analyse in details the imaging study and the clinical data. In most cases, an endocrine work-up is warranted including measurement of cathecholamines/ metanephrines (even in the absence of hypertension) and an overnight 1 mg dexamethasone suppression test. Additional analyses will depend on clinical data (aldosterone and renin in hypertensive patients ; DHEAS in case of hyperandrogenism) or on imaging (17 hydroxyprogesterone in bilateral lesions). The results have to be interpretated in light of the pre-test probability of endocrine dysfunction.
UCLouvain(MGD) Service de médecine interne générale - endocrinologie
Citations
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Delgrange, E. (2013). Incidentalome surrénalien : Quel bilan hormonal pour quelle rentabilité ? Louvain médical, 132(3), 135-137. https://hdl.handle.net/2078.5/186072 (Original work published 2013)