Engineering of non-natural receptors

Mathonet, P;Fastrez, Jacques
(2004) Current Opinion in Structural Biology — Vol. 14, n° 4, p. 505-511 (2004)

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Authors
  • Mathonet, P
    Author
  • Fastrez, JacquesUCLouvain
    Author
Abstract
Rational design, usually guided by computational prediction, and selection from libraries of variants of natural proteins have been used with success in the engineering of novel non-natural receptors. Many of these engineered protein binders will find use in biotechnological, diagnostic and medical applications, sometimes in the place of natural antibodies.
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Mathonet, P., & Fastrez, J. (2004). Engineering of non-natural receptors. Current Opinion in Structural Biology, 14(4), 505-511. https://doi.org/10.1016/j.sbi.2004.06.007 (Original work published 2004)