Sildenafil therapy for neonatal and childhood pulmonary hypertensive vascular disease.

Humpl, Tilman;Reyes, Janette T;Erickson, Simon;Armano, Ruth;Adatia, Ian;et.al.
(2011) Cardiology in the Young — Vol. 21, n° 2, p. 187-193 (2011)

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Authors
  • Humpl, Tilman
    Author
  • Reyes, Janette T
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  • Erickson, Simon
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  • Armano, RuthUCLouvain
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  • Adatia, Ian
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Abstract
In children under 5 years of age with severe pulmonary hypertension, sildenafil therapy resulted in prolonged hemodynamic improvements without adverse effects. Sildenafil attenuated rebound pulmonary hypertension after withdrawal of inhaled nitric oxide.
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Humpl, T., Reyes, J. T., Erickson, S., Armano, R., Holtby, H., & Adatia, I. (2011). Sildenafil therapy for neonatal and childhood pulmonary hypertensive vascular disease. Cardiology in the Young, 21(2), 187-193. https://doi.org/10.1017/S1047951110001745 (Original work published 2011)