Introduction: Large monocentric series of laparoscopic pancreatic resection (LPR) are still lacking. This series studied evolution of indications and outcome of LPR. Methods: This is a retrospective monocentric study. Main contraindications were major vascular invasion and pancreatitis. Demographics, surgical, and postoperative outcome data were studied. We compared the first 350 LPR (2008-2016) and the last 350 LPR (2017-2020). Results: From 2008 to 2020, 700 LPR were performed including 191 PD (27%), 344 DP (50%), 92 CP (13%), 69 Enucleation (10%) and 4 TP (1%). The applicability of laparoscopy increased from 10% before 2010 to 40% in 2020. Mean age and BMI were 56 (17-87) and 25 kg/m2 (15-48), respectively and 406 were female (58%).The main indications: IPMN (169; 24%), NET (167; 24%) and pancreatic adenocarcinoma (124, 18%). The surgical outcomes showed conversion (3%), mean operative duration (207; 30-540 mn), blood loss (213; 0-2500 ml), transfusion (4%), mortality (9; 1.3%), overall morbidity (56%), POPF B/C (19%), bleeding (7%), re-intervention (7%), readmission (6%) and mean hospital stay 16(2-104). The second period versus the first period showed more comorbidities (39% vs 52%; p<0.0001), less noninvasive IPMN (39% vs 18%; p<0.001, less splenectomy (17% vs 9%,p=0.002), less conversion (4% vs 2%,p=0.046), less POPF (24% vs 15%,p=0.001), less bleeding (9% vs 5%,p=0.036), less re-intervention (10% vs 5%,p=0.004) and a shorter hospital stay (18 vs 13; p<0.001). Conclusion: This large series including all types of pancreatic resections showed more patients with comorbidities and evolution in the indications. The good outcome is furthermore improved with the experience.
Aussilhou, B., Ftériche, F. S., Cauchy, F., Marique, L., Sauvanet, A., & Dokmak, S. (2022). 700 Laparoscopic Pancreatic Resections in a French Center: Evolution of the Indications and Outcome. HPB : the official journal of the International Hepato Pancreato Biliary Association, 24, S363-S364. https://doi.org/10.1016/j.hpb.2022.05.769 (Original work published 2022)