The papillary carcinoma is the most common cancer of thyroid but its presentation may be unexpected. In the first case, a 18-year-old girl complained of a painful enlargement of the right thyroid lobe. Upon the basis of a CT scan revealing punctuate calcifications suggesting psammoma bodies and a right-sided cold nodule on thyroid radioiodine scanning, the patient had a thyroidectomy. The second case was a discovery of papillary carcinoma in a 49-year-old woman who had a thyroidectomy for Graves' disease. This association may not be fortuitous. The cancer could be more aggressive in this group of patients, as TSI play a pathogenic role.
Heureux, F., Michel, L., Trigaux, J.-P., Delos, M., & Donckier, J. (1996). Unusual presentation of papillary thyroid carcinoma: about two cases. Acta Clinica Belgica (Multilingual Edition), 51(3), 166-169. https://hdl.handle.net/2078.5/135366 (Original work published 1996)