Cues and sensory manipulations to modulate long-range autocorrelations in gait variability among patients with Parkinson's disease
(2024)
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- Authors
- Supervisors
- Lejeune, Thierry
- Abstract
- Parkinson's disease causes gait disorders in terms of both spatiotemporal parameters (speed, step length, cadence) and variability (magnitude, temporal organization), increasing the risk of falls and their consequences. The use of external stimuli (tactile, auditory, visual) is recommended to treat these disorders. These "cueings" have positive effects on spatiotemporal parameters, but there are many questions concerning their impact on the temporal organization of patients' gait, measured via long-range autocorrelations (LRA) computation. In this thesis, the patients' senses were manipulated (touch, hearing, vision) to determine their effects on the LRA present in their gait. Firstly, tactile cueing showed similar effects to auditory cueing on patients' LRA. With regard to auditory cueing, we have established that a cueing frequency that fluctuates according to a structured variability may be the best choice for maintaining a good level of LRA. Concerning vision, virtual reality makes it easy to manipulate visual feedbacks. Via a systematic review of the literature with meta-analysis, we showed that virtual reality is effective in improving patients' balance. Next, we manipulated patients' vision by adding natural optic flow in immersive virtual reality during treadmill walking. This ecological addition enabled us to restore LRA similar to those measured during overground walking, possibly increasing the validity of this measurement when analyzing it in a laboratory setting.
- Affiliations
Citations
Lheureux, A. (2024). Cues and sensory manipulations to modulate long-range autocorrelations in gait variability among patients with Parkinson’s disease. https://hdl.handle.net/2078.5/29788