The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

El Bardai, Sanae;Morel, Nicole;Wibo, Maurice;Fabre, Nicolas;Quetin-Leclercq, Joëlle;et.al.
(2003) Planta Medica : natural products and medicinal plant research — Vol. 69, n° 1, p. 75-77 (2003)

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Authors
  • El Bardai, SanaeUCLouvain
    Author
  • Morel, NicoleUCLouvain
    Author
  • Wibo, MauriceUCLouvain
    Author
  • Fabre, NicolasUCLouvain
    Author
  • Quetin-Leclercq, JoëlleUCLouvain
    Author
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Abstract
Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
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El Bardai, S., Morel, N., Wibo, M., Fabre, N., Llabres, G., Lyoussi, B., & Quetin-Leclercq, J. (2003). The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare. Planta Medica : natural products and medicinal plant research, 69(1), 75-77. https://doi.org/10.1055/s-2003-37042 (Original work published 2003)