Case report of multiple rectal neuroendocrine tumors in a context of ulcerative colitis.
(2022) International Journal of Surgery Case Reports — Vol. 91, n° 1, p. 106760 (2022)
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- Abstract
- Neuroendocrine tumors (NETs) of the rectum are rare, with an estimated incidence of 0.1% of all colorectal cancers. However, it is crucial to diagnose NET, particularly in patients with ulcerative colitis, who seem to have a higher risk of cancerization according to recent studies, given the aggressiveness and poor prognosis of these tumors. We report the case of a 54-year-old man who developed multiple rectal NETs (approximately 10), measuring 1-6 mm, only 2 years after a primary diagnosis of ulcerative colitis. In the literature, all reported cases of NETs present patients with a long history of several years of inflammatory bowel disease; however, very little literature exists on this subject. Herein, we discussed the outcomes and a literature review of the pathology, prognosis, and management of NETs. Despite advances in research on rectal NETs, many aspects about the disease remain unclear, partly due to its rarity.
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Manhal, K., Christophe, R., Radu, B., Daniel, L., Jeremy, S., & Alex, K. (2022). Case report of multiple rectal neuroendocrine tumors in a context of ulcerative colitis. International Journal of Surgery Case Reports, 91(1), 106760. https://doi.org/10.1016/j.ijscr.2022.106760 (Original work published 2022)