Research on psychedelic substances such as lysergic acid diethylamide (LSD), psilocybin, and dimethyltryptamine (DMT) is gaining momentum.1 However, the possible effects of these substances on systemic functions such as endocrine activity, particularly neurotransmitter-regulated glucagon release in pancreatic alpha cells, remain largely unexplored. This commentary aims to address the unprecedented subject of how psychedelics might alter neurotransmitter concentrations involved in both intra-islet and extra-islet signalling, thereby impacting glucagon release. [...]
Bostanciklioglu, M. (2024). Exploring new frontiers: Effects of psychedelics on neurotransmitter-regulated glucagon release in pancreatic islets. Diabetes, obesity & metabolism, 26(4), 1147-1149. https://doi.org/10.1111/dom.15411 (Original work published 2024)