Muscle carnosine and its methylated form anserine are histidine-containing dipeptides. Both dipeptides have the ability to quench reactive carbonyl species and previous studies have shown that endogenous tissue levels are decreased in chronic diseases, such as diabetes.
Stegen, S., Everaert, I., Deldicque, L., Vallova, S., de Courten, B., Ukropcova, B., Ukropec, J., & Derave, W. (2015). Muscle histidine-containing dipeptides are elevated by glucose intolerance in both rodents and men. PLoS One, 10(3), e0121062. https://doi.org/10.1371/journal.pone.0121062 (Original work published 2015)