Alpha-methyl Amino-acids By Catalytic Phase-transfer Alkylations
(1982) Tetrahedron Letters — Vol. 23, n° 41, p. 4259-4262 (1982)
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- Authors
Antoine, Jean-Pierre 
- Abstract
- The α-methyl amino acids, α-methyl p-chlorophenylalanine, α-methyl p-tyrosine, α-methyl m-tyrosine and α-methyl DOPA have been prepared in good yields from amino ester hydrochlorides. The key step in the method is the catalytic phase-transfer alkylation of Schiff base derivatives of mono alkyl amino acids.
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Citations
O’donnell, M. J., Leclef, B., Rusterholz, D. B., Ghosez, L., Antoine, J.-P., & Navarro, M. (1982). Alpha-methyl Amino-acids By Catalytic Phase-transfer Alkylations. Tetrahedron Letters, 23(41), 4259-4262. https://doi.org/10.1016/S0040-4039(00)88719-5 (Original work published 1982)