Microsomal vinyl oxide synthetase: modification of its kinetic parameters by chemical carcinogens.
(1979) Archives of Toxicology. Supplement — n° 2, p. 465-469 (1979)
Files
No attached file found for this publication.
Details
- Authors
- Abstract
- The kinetic parameters of liver microsomal vinyl oxide synthetase as well as their modifications under the influence of various pretreatments have been evaluated, using 1,1,2-trichlorethylene (TCE) as a substrate. The results were correlated with those obtained using aldrin oxide synthetase and benzpyrene hydroxylase as typical cytochrome P-450 dependent enzymatic activity. The treatments of animals with chemical carcinogens selectively increase the affinity of those enzymes for their substrates.
- Affiliations
Citations
Malvoisin, E., Roberfroid, M., & Mercier, M. (1979). Microsomal vinyl oxide synthetase: modification of its kinetic parameters by chemical carcinogens. Archives of Toxicology. Supplement, 2, 465-469. https://hdl.handle.net/2078.5/135337 (Original work published 1979)