Prescripción del tratamiento antimalárico en pacientes con malaria no complicada por P. vivax en Putumayo. Colombia
(2011) Medicina & Laboratorio — Vol. 17, p. 445-455 (2011)
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- Authors
Rosas Aguirre, Angel 
- Abstract
- (en) Introduction: Chloroquine (CQ, 25 mg/kg in total: 10 mg/ kg on the first day and 7,5 mg/kg on the second and third days) and Primaquine (PQ, 3,5 mg/kg for 14 days) are recommended for P. vivax malaria treatment. Objective: To assess antimalarial treatment prescriptions in patients with P. vivax malaria in Putumayo, Colombia. Materials and methods: Between February 2009 and February 2010, antimalarial treatment prescriptions in patients with P. vivax malaria were evaluated in ten health facilities of two municipalities (Puerto Asís and Puerto Guzmán). Appropriate prescription of CQ should include a total dose of 23,8 to 30,0 mg base/kg and appropriate prescription of PQ should include a total dose of 3,3 to 4,2 mg base/kg. An appropriate global prescription should include both appropriate total doses. Results: Prescriptions from 136 patients were evaluated, 52 through direct observations of prescription practices during patient attention, and 84 through revision of treatment records; 82 (60,3%) patients had appropriate dosage of CQ, 32 (23,5%) had under-dosage, and 22 (16,2%) had over-dosage. With respect to prescribed PQ, 79 (58,1%) patients had appropriate dosage, 17 (12,5%) had underdosage, and 40 (29,4%) had over-dosage. More than half of the global prescriptions (CQ+PQ) were inappropriate. Inappropriate prescriptions (CQ and/or PQ) were higher in patients younger than 15 years, while the under-dosage was higher in patients with weights over 60 kg. Conclusion: Poor prescriptions pose a serious problem to get effective management of P. vivax infections in Putumayo
- Affiliations
Universidad Peruana Cayetano Heredia, Lima, Perú
Citations
Rosas Aguirre, A., Milena Briceño, A., Moreno, D., Vargas, D., & Acuña, Y. (2011). Prescripción del tratamiento antimalárico en pacientes con malaria no complicada por P. vivax en Putumayo. Colombia. Medicina & Laboratorio, 17, 445-455. https://hdl.handle.net/2078.5/98984 (Original work published 2011)