The available data on carbohydrate metabolism in Kinetoplastida have been reviewed. Based on the metabolic pattern of different kinetoplastid organisms, on the subcellular distribution of their glycolytic enzymes, and on the structural and regulatory properties of these proteins, we propose that the glycosome developed from an endosymbiont, as a specific manner to control carbohydrate and energy metabolism. It is discussed how the enzymes were subcellularly recompartmentalized during evolution as adaptation to the environment encountered by the organisms.
Michels, P., & Hannaert, V. (1994). The evolution of kinetoplastid glycosomes. Journal of Bioenergetics and Biomembranes, 26(2), 213-219. https://doi.org/10.1007/BF00763070 (Original work published 1994)