A rat gene encoding heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
(1991) FEBS Letters — Vol. 288, n° 1-2, p. 91-94 (1991)
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- Abstract
- There are at least 3 isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, a bifunctional enzyme which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate. A 22-kb rat gene that encodes the heart isozyme has been identified and compared with the 55-kb rat gene encoding the liver and muscle isozymes which had been described earlier. Although these 2 genes include 12 successive similar exons, they contain dissimilar exons at both ends, consistent with the occurrence of different regulatory domains at the N- and C-termini in the 3 isozymes.
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Darville, M. I., Chikri, M., Lebeau, E., Hue, L., & Rousseau, G. (1991). A rat gene encoding heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. FEBS Letters, 288(1-2), 91-94. https://doi.org/10.1016/0014-5793(91)81009-W (Original work published 1991)