Diagnosis of hepatitis C-related liver disease in patients with mild hemophilia.

Krumb, Evelien;Lambert, Catherine;Horsmans, Yves;Hermans, Cédric
(2021) European Journal of Internal Medicine — Vol. 91, p. 102-103 (2021)

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Following the contamination of blood products with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) in the 1970s to 1980s, almost all hemophilia patients who received plasma-derived factor products were infected with HCV prior to the implementation of viral inactivation in 1985. Of these patients, around 20% spontaneously cleared the virus. The remainder developed chronic hepatitis and around 30% of them cirrhosis and finally hepatocellular carcinoma (HCC) in the absence of treatment. [...]
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Krumb, E., Lambert, C., Horsmans, Y., & Hermans, C. (2021). Diagnosis of hepatitis C-related liver disease in patients with mild hemophilia. European Journal of Internal Medicine, 91, 102-103. https://doi.org/10.1016/j.ejim.2021.05.033 (Original work published 2021)