Successful management of hereditary angioedema during tonsillectomy: a case report
(2012) Blood Coagulation and Fibrinolysis — Vol. 23, n° 2, p. 155-157 (2012)
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- Abstract
- Hereditary angioedema (HAE) is a rare genetic disorder causing a deficiency in C1 esterase inhibitor (C1-INH) that is manifested through unpredictable oedema. We describe a case of a patient with HAE who had previously been refused surgery for tonsillitis due to the potential for oedema, in whom regular monitoring of C1-INH levels combined with intensified therapy with danazol, tranexamic acid and C1-INH concentrate enabled an uncomplicated procedure with no oedema crisis. However, clinicians should be alerted that higher overall dosages of C1-INH concentrate for perioperative prophylaxis may be required than those typically used to treat acute HAE attacks.
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Hermans, C., Van Der Vorst, S., & Lambert, C. (2012). Successful management of hereditary angioedema during tonsillectomy: a case report. Blood Coagulation and Fibrinolysis, 23(2), 155-157. https://doi.org/10.1097/MBC.0b013e32834ee10d (Original work published 2012)