TEM, FCM and filtration coupled to TGA represent a useful combination to study the PCA of TF-bearing microvesicles, whatever their size. And it will be interesting to implement these techniques in patients.
Gheldof, D., Hardij, J., Cecchet, F., Chatelain, B., Dogné, J.-M., & Mullier, F. (2013). Thrombin generation assay and transmission electron microscopy: a useful combination to study tissue factor-bearing microvesicles. Journal of Extracellular Vesicles, 2. https://doi.org/10.3402/jev.v2i0.19728 (Original work published 2013)