A 4-year trial of tiotropium in chronic obstructive pulmonary disease.

Tashkin, Donald P;Celli, Bartolome;Senn, Stephen;Burkhart, Deborah;Delaunois, Luc;et.al.
(2008) New England Journal of Medicine — Vol. 359, n° 15, p. 1543-1554 (2008)

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Authors
  • Tashkin, Donald P
    Author
  • Celli, Bartolome
    Author
  • Senn, Stephen
    Author
  • Burkhart, Deborah
    Author
  • Delaunois, LucUCLouvain
    Collaborator
  • et. al.
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Abstract
In patients with COPD, therapy with tiotropium was associated with improvements in lung function, quality of life, and exacerbations during a 4-year period but did not significantly reduce the rate of decline in FEV(1). (ClinicalTrials.gov number, NCT00144339.)
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Tashkin, D. P., Celli, B., Senn, S., Burkhart, D., Kesten, S., Menjoge, S., Decramer, M., UPLIFT Trial, & et al. (2008). A 4-year trial of tiotropium in chronic obstructive pulmonary disease. New England Journal of Medicine, 359(15), 1543-1554. https://doi.org/10.1056/NEJMoa0805800 (Original work published 2008)